Nutlin 3a | Tocris Bioscience 6075 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Nutlin 3a

catalog :

6075

quantity :

25 mg

price :

822 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6075

SKU :

6075/25

product name :

Nutlin 3a

description :

MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

97%

observed molecular weight :

581.49

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MDM2 antagonist (IC50 = 90 nM); inhibits the MDM2-p53 interaction. Active enantiomer of Nutlin-3 (Cat. No. 3984). Induces expression for P53 regulated genes. Suppresses tumor growth in vivo 98% in prostate cancer and osteosarcoma cancer models. Antiproliferative.

catalog number base :

6075

product keywords :

Nutlin3a p53 activators MDM2 antagonism antagonists p53-MDM2 activates Ubiquitin E3 Ligases p53 6075, E3 Ligase

extended description :

MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)

chemical name text :

4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone

formula :

C 30 H 30 Cl 2 N 4 O 4

formula text :

C30H30Cl2N4O4

cas num :

675576-98-4

2020 USD :

790

2021 USD :

822 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage