CZC 25146 | Tocris Bioscience 6071/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CZC 25146

catalog :

6071/10

quantity :

10 mg (also 50 mg)

price :

263 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6071 - CZC 25146 C22H25FN6O4S CAS No. 1191911-26-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6071

SKU :

6071/10

product name :

CZC 25146

description :

Potent LRRK2 inhibitor

target :

LRRK2 Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

488.54

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CZC 25146 is a potent LRRK2 inhibitor (IC50 values are 4.76 and 6.87 nM for for wild-type and G2019S mutant forms of LRRK2, respectively). Also inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2. Attenuates mutant LRRK2-induced injury of cultured rodent and human neurons. Cell permeable.

product keywords :

CZC25146 leucine-rich repeat kinase 2 LRRK2 inhibitors inhibits potent neuroprotective neuronal injury parkinson's parkinsons LRRK2 6071, LRRK 2

extended description :

Potent LRRK2 inhibitor

chemical name text :

N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide

formula :

C22H25FN6O4S

formula text :

C22H25FN6O4S

cas num :

1191911-26-8

USD :

292

USD 2025 :

263 USD

product details :

Potent LRRK2 inhibitor

more info or order :

Tocris Bioscience product webpage