XMD 8-87 | Tocris Bioscience 6061 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

XMD 8-87

catalog :

6061

quantity :

10 mg (also 50 mg)

price :

183 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6061

SKU :

6061/10

product name :

XMD 8-87

description :

Potent Ack1/TNK2 inhibitor

target :

Ack1 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

445.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Ack1/TNK2 inhibitor (IC50 = 38 and 113 nM in Ba/F3 cell lines containing leukemia-associated D163E and R806Q mutations respectively). Blocks phosphorylation of TNK2 receptors containing solid-tumor type truncation mutations.

catalog number base :

6061

product keywords :

XMD8-87 Inhibitors inhibits Ack1 TNK2 Ba/F3 leukemia D163E R806Q phosphorylation tyrosine kinase 2 Ack1 6061,

extended description :

Potent Ack1/TNK2 inhibitor

chemical name text :

5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

formula :

C 24 H 27 N 7 O 2

formula text :

C24H27N7O2

cas num :

1234480-46-6

2020 USD :

203

2021 USD :

183 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage