AZD 2461 | Tocris Bioscience 6060/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 2461

catalog :

6060/10

quantity :

10 mg (also 50 mg)

price :

120 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6060 - AZD 2461 C22H22FN3O3 CAS No. 1174043-16-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6060

SKU :

6060/10

product name :

AZD 2461

description :

Potent PARP inhibitor; orally bioavailable

target :

Poly(ADP-ribose) Polymerase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

395.43

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZD 2461 is a potent PARP inhibitor (IC50 values are 2, 5 and 200 nM for PARP2, PARP1 and PARP3, respectively). Exhibits anticancer effects in BRCA1 mutant, but not wild-type breast cancer cell lines in vitro . Inhibits growth of olaparib -resistant mammary tumors in a mouse model and is a poor substrate for the P-gp transporter. Orally bioavailable.

product keywords :

AZD2461 potent PARP inhibitors inhibits poly (ADP-ribose) polymerases orally bioavailable chemotherapeutics Poly(ADP-ribose) Polymerase 6060,

extended description :

Potent PARP inhibitor; orally bioavailable

chemical name text :

4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone

formula :

C22H22FN3O3

formula text :

C22H22FN3O3

cas num :

1174043-16-3

USD :

133

USD 2025 :

120 USD

product details :

Potent PARP inhibitor; orally bioavailable

more info or order :

Tocris Bioscience product webpage