product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ATN 161
catalog :
6058/10
quantity :
10 mg
price :
293 USD
more info or order :
Tocris Bioscience product webpage
citations: 5
Reference
Masi I, Ottavi F, Del Rio D, Caprara V, Vastarelli C, Giannitelli S, et al. The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer. Cell Death Dis. 2023;14:73 pubmed publisher
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al. Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. elife. 2020;9: pubmed publisher
Asare Werehene M, Nakka K, Reunov A, Chiu C, Lee W, Abedini M, et al. The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance. Oncogene. 2020;39:1600-1616 pubmed publisher
DeRita R, Sayeed A, Garcia V, Krishn S, Shields C, Sarker S, et al. Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth. iScience. 2019;14:199-209 pubmed publisher
Albarrán Juárez J, Iring A, Wang S, Joseph S, Grimm M, Strilic B, et al. Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation. J Exp Med. 2018;215:2655-2672 pubmed publisher
product information
brand :
Tocris
catalog number base :
6058
SKU :
6058/10
product name :
ATN 161
units size :
10 mg
description :
5 1 integrin receptor antagonist
target :
Integrin Receptor Inhibitors
category :
Peptides
purity :
95%
observed molecular weight :
597.65
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
ATN 161 is a 5 1 integrin receptor antagonist. Reduces liver metastasis and improves survival in combination with 5-FU (Cat. No. 3257) in a mouse model of colon cancer. Reduces MLL tumor growth in rats and decreases tumor volume of human MDA-MB-231 cell xenografts in mice.
top caption :
5 1 integrin receptor antagonist
extended description :
5 1 integrin receptor antagonist
formula :
C23H35N9O8S
formula text :
C23H35N9O8S
cas num :
262438-43-7
USD :
293 USD
product details :
5 1 integrin receptor antagonist
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK