GSK 1363089 | Tocris Bioscience 6056 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 1363089

catalog :

6056

quantity :

10 mg (also 50 mg)

price :

177 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6056

SKU :

6056/10

product name :

GSK 1363089

description :

Potent inhibitor of MET, VEGFR2, Ron and AXL

target :

MET Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

632.65

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of MET, VEGFR2, Ron and AXL (IC50 values are 0.4, 0.9, 3 and 11 nM, respectively). Also potently inhibits Tie-2, Flt-1, Flt-3, Flt-4, KIT, PDGFR and PDGFR . Inhibits migration and invasion of B16F10 melanoma cells in vitro . Suppresses B16F10 tumor growth and metastasis in mice. Orally available.

catalog number base :

6056

product keywords :

GSK1363089 potent inhibitors inhibits HGF VEGFR2 AXL tyrosine kinases orally available XL880 EXEL2880 XL 880 EXEL 2880 Foretinib MET Receptors VEGFR FLT3 PDGFR 6056,

extended description :

Potent inhibitor of MET, VEGFR2, Ron and AXL

chemical name text :

N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N -(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

formula :

C 34 H 34 F 2 N 4 O 6

formula text :

C34H34F2N4O6

cas num :

849217-64-7

2020 USD :

173

2021 USD :

177 USD

alt names :

XL 880, EXEL 2880, Foretinib

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage