product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BAY 58-2667 hydrochloride
catalog :
6052/10
quantity :
10 mg
price :
305 USD
more info or order :
citations: 2
Reference
Zagorski J, Neto Neves E, Alves N, Fisher A, Kline J. Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis. Physiol Rep. 2022;10:e15156 pubmed publisher
Cheng D, Talib J, Stanley C, Rashid I, Michaëlsson E, Lindstedt E, et al. Inhibition of MPO (Myeloperoxidase) Attenuates Endothelial Dysfunction in Mouse Models of Vascular Inflammation and Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019;39:1448-1457 pubmed publisher
image
image 1 :
Tocris Bioscience 6052/10 image 1
Cat.No. 6052 - BAY 58-2667 hydrochloride C36H39NO5.HCl CAS No. 646995-35-9
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6052
SKU :
6052/10
product name :
BAY 58-2667 hydrochloride
description :
Potent soluble guanylyl cyclase (sGC) activator
target :
Guanylyl Cyclase Activators
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
602.16
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BAY 58-2667 hydrochloride is a potent soluble guanylyl cyclase (sGC) activator (EC50 = 6.4 nM). Binds heme-free sGC. Exhibits antihypertensive effects in vivo .
product keywords :
BAY58-2667 hydrochloride potent soluble guanylyl cyclase activators activates antihypertensive Cinaciguat hydrochloride Guanylyl Cyclase Enzyme Substrates/ Activators 6052,
extended description :
Potent soluble guanylyl cyclase (sGC) activator
chemical name text :
4-[[(4-Carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride
formula :
C36H39NO5.HCl
formula text :
C36H39NO5.HCl
cas num :
646995-35-9
USD :
296
USD 2025 :
305 USD
product details :
Potent soluble guanylyl cyclase (sGC) activator
alt names :
Cinaciguat hydrochloride
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK