chemical

SR 10067

6038/10

10 mg (also 50 mg)

183 USD

6038

6038/10

0.0006

SR 10067

Selective Rev-Erb / agonist; anxiolytic

Nuclear Receptor Agonists

Small Molecules

10 mg (also 50 mg)

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SR 10067 is a selective Rev-Erb / agonist (IC50 values are 160 and 170 nM for Rev-Erb and Rev-Erb respectively). Exhibits no significant activity against a wide range of nuclear receptors, other receptors, ion channels and transporters at 20 M. Increases wakefulness, reduces REM and slow wave sleep in vivo . Also reduces anxiety-like behavior in marble-burying assay. Cell permeable and brain penetrant.

Selective Rev-Erb / agonist; anxiolytic

[3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone

C 31 H 31 NO 3

C31H31NO3

1380548-02-6

183 USD

Selective Rev-Erb / agonist; anxiolytic

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.