product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(R)-MG 132
catalog :
6033/10
quantity :
10 mg
price :
397 USD
more info or order :
citations: 3
Reference
Dematteis G, Restelli E, Vanella V, Manfredi M, Marengo E, Corazzari M, et al. Calcineurin Controls Cellular Prion Protein Expression in Mouse Astrocytes. Cells. 2022;11: pubmed publisher
Dematteis G, Restelli E, Chiesa R, Aronica E, Genazzani A, Lim D, et al. Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation. Int J Mol Sci. 2020;21: pubmed publisher
Koncar R, Dey B, Stanton A, Agrawal N, Wassell M, McCarl L, et al. Identification of novel RAS signaling therapeutic vulnerabilities in Diffuse Intrinsic Pontine Gliomas. Cancer Res. 2019;: pubmed publisher
image
image 1 :
Tocris Bioscience 6033/10 image 1
Cat.No. 6033 - (R)-MG 132 C26H41N3O5 CAS No. 1211877-36-9
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6033
SKU :
6033/10
product name :
(R)-MG 132
description :
Potent 20S proteasome inhibitor
target :
Proteasome Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
475.63
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( R )-MG 132 is a potent 20S proteasome inhibitor (IC50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro .
product keywords :
(R)-MG132 20S proteasome inhibitors inhibits potent Proteasome 6033,
extended description :
Potent 20S proteasome inhibitor
chemical name text :
N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide
formula :
C26H41N3O5
formula text :
C26H41N3O5
cas num :
1211877-36-9
USD :
385
USD 2025 :
397 USD
product details :
Potent 20S proteasome inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK