RAF 265 | Tocris Bioscience 6015 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

RAF 265

catalog :

6015

quantity :

10 mg (also 50 mg)

price :

207 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6015

SKU :

6015/10

product name :

RAF 265

description :

Raf kinase and VEGFR-2 inhibitor

target :

Raf Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

518.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Raf kinase and VEGFR-2 inhibitor. Inhibits c-Raf, wild type B-Raf and mutant B-Raf (V600E). Cytotoxic in certain melanoma cells lines. Effects enhanced by protein kinase D3 inhibition, preventing reactivation of MAPK signaling and increasing caspase activity. Orally bioavailable.

catalog number base :

6015

product keywords :

RAF265 Raf kinases inhibitors inhibits B-Raf c-Raf VEGFR2 vascular endothelial growth factor cytotoxic MAPK CHIR 265 Raf Kinase VEGFR 6015,

extended description :

Raf kinase and VEGFR-2 inhibitor

chemical name text :

1-Methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine

formula :

C 24 H 16 F 6 N 6 O

formula text :

C24H16F6N6O

cas num :

927880-90-8

2020 USD :

207

2021 USD :

207 USD

alt names :

CHIR 265

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage