OXSI 2 | Tocris Bioscience 6012 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

OXSI 2

catalog :

6012

quantity :

10 mg (also 50 mg)

price :

185 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6012

SKU :

6012/10

product name :

OXSI 2

description :

Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes

target :

Syk Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

353.39

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Syk kinase inhibitor (IC50 = 14 nM). Inhibits assembly of NLRP3 inflammasomes induced by Nigericin (Cat.No. 4312). Also inhibits the activation of caspase-1, IL-1 processing and release, mitochondrial ROS generation and pyroptic cell death in mouse macrophage cells.

catalog number base :

6012

product keywords :

OXSI2 Inhibitors inhibits Syk kinase NLRPL3 inflammasome caspase-1 IL-1beta IL-1b IL-1 mitochondria ROS pyroptosis inflammation Syk Kinase Inflammasomes 6012,

extended description :

Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes

chemical name text :

2,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2-oxo-1H-indole-5-sulfonamide

formula :

C 18 H 15 N 3 O 3 S

formula text :

C18H15N3O3S

cas num :

622387-85-3

2020 USD :

181

2021 USD :

185 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage