B I09 | Tocris Bioscience 6009/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

B I09

catalog :

6009/10

quantity :

10 mg (also 50 mg)

price :

294 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zundell J, Fukumoto T, Lin J, Fatkhudinov N, Nacarelli T, Kossenkov A, et al. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers. Cancer Res. 2021;81:5325-5335 pubmed publisher

image

image 1 :

Cat.No. 6009 - B I09 C16H17NO5 CAS No. 1607803-67-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6009

SKU :

6009/10

product name :

B I09

description :

IRE1 endonuclease inhibitor; cell permeable

target :

IRE1 Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

303.31

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

B I09 is an IRE-1 RNase inhibitor (IC50 = 1.23 M). Inhibits IRE-1/XBP1 pathway. Cell permeable. Inhibits growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model.

product keywords :

BI09 IRE inhibitors inhibits cell permeable in vivo active RNAse endonuclease IRE1 IRE1 6009,

extended description :

IRE1 endonuclease inhibitor; cell permeable

chemical name text :

7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one

formula :

C16H17NO5

formula text :

C16H17NO5

cas num :

1607803-67-7

USD :

282

USD 2025 :

294 USD

product details :

IRE1 endonuclease inhibitor; cell permeable

more info or order :

Tocris Bioscience product webpage