TP 064 | Tocris Bioscience 6008 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TP 064

catalog :

6008

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhong X, Yuan X, Xu Y, Yin M, Yan W, Zou S, et al. CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer. Cell Rep. 2018;24:3207-3223 pubmed publisher

product information

brand :

Tocris

master code :

6008

SKU :

6008/10

product name :

TP 064

description :

Potent and selective PRMT 4 inhibitor

target :

Protein Arginine Methyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

458.6

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective PRMT4 inhibitor; inhibits methylation of H3 (1-25) and MED12 (IC50 values are 10 and 43 nM, respectively). Exhibits 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. Inhibits proliferation of certain multiple myeloma cell lines, arresting cells in G1 phase. . To request the negative control for TP 064, please fill out the TP 064N request form on the SGC website.

catalog number base :

6008

product keywords :

TP064 Potent allosteric inhibitors inhibits of protein arginine methyltransferase 4 PRMT4 methylation Protein Arginine Methyltransferases 6008,

extended description :

Potent and selective PRMT 4 inhibitor

chemical name text :

N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide

formula :

C 28 H 34 N 4 O 2

formula text :

C28H34N4O2

cas num :

2080306-20-1

2020 USD :

145

2021 USD :

151 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage