PF 3758309 dihydrochloride | Tocris Bioscience 6005 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 3758309 dihydrochloride

catalog :

6005

quantity :

10 mg (also 50 mg)

price :

92 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6005

SKU :

6005/10

product name :

PF 3758309 dihydrochloride

description :

Potent PAK4 inhibitor; orally available

target :

PAK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

563.55

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent PAK4 inhibitor (IC50 = 1.3 nM; Kd = 2.7 nM). Inhibits proliferation and anchorage-independent growth of a panel of tumor cell lines in vitro . Suppresses growth of human HCT116 and A549 tumor cell xenografts in mice. Orally available.

catalog number base :

6005

product keywords :

PF3758309 dihydrochloride Potent PAK4 inhibitors inhibits orally available 89044_15_0 chemical probes P21-activated Kinases 6005, p21-Activated Kinases, p21-Activated Kinase, PAKs

extended description :

Potent PAK4 inhibitor; orally available

chemical name text :

N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride

formula :

C 25 H 30 N 8 OS.2HCl

formula text :

C25H30N8OS.2HCl

2020 USD :

114

2021 USD :

92 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage