PF 06281355 | Tocris Bioscience 6004/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 06281355

catalog :

6004/10

quantity :

10 mg (also 50 mg)

price :

190 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6004 - PF 06281355 C14H15N3O4S CAS No. 1435467-38-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6004

SKU :

6004/10

product name :

PF 06281355

description :

Selective myeloperoxidase (MPO) inhibitor

target :

Other Oxidase/Oxygenase Compounds

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

321.35

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 06281355 is a selective myeloperoxidase (MPO) inhibitor (IC50 = 1.5 M in LPS-stimulated human whole blood). Selective for MPO over a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. Inhibits MPO activity in peritoneal lavage and plasma in a murine peritonitis model. Also reduces lung edema in a murine pulmonary immune complex vasculitis model. Orally bioavailable.

product keywords :

PF06281355 myeloperoxidase inhibitors inhibits selective orally bioavailable vasculitis Other Oxygenases/Oxidases 6004,

extended description :

Selective myeloperoxidase (MPO) inhibitor

chemical name text :

6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide

formula :

C14H15N3O4S

formula text :

C14H15N3O4S

cas num :

1435467-38-1

USD :

211

USD 2025 :

190 USD

product details :

Selective myeloperoxidase (MPO) inhibitor

more info or order :

Tocris Bioscience product webpage