product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ZQ 16
catalog :
6001
quantity :
10 mg (also 50 mg)
price :
84 USD
more info or order :
citations: 1
Reference
Sundqvist M, Christenson K, Holdfeldt A, Gabl M, Mårtensson J, Björkman L, et al. Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R. Biochim Biophys Acta Mol Cell Res. 2018;1865:695-708 pubmed publisher
product information
brand :
Tocris
master code :
6001
SKU :
6001/10
product name :
ZQ 16
description :
Selective GPR84 agonist
target :
Free Fatty Acid Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
228.31
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 M. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro .
catalog number base :
6001
product keywords :
ZQ16 selective medium chain free fatty acid receptor GPR84 agonists agonism Free Fatty Acid Receptors 6001,
extended description :
Selective GPR84 agonist
chemical name text :
2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
formula :
C 10 H 16 N 2 O 2 S
formula text :
C10H16N2O2S
cas num :
376616-73-8
2020 USD :
104
2021 USD :
84 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK