Enzastaurin | Tocris Bioscience 5994 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Enzastaurin

catalog :

5994

quantity :

10 mg (also 50 mg)

price :

145 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5994

SKU :

5994/10

product name :

Enzastaurin

description :

Potent PKC inhibitor

target :

Protein Kinase C Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

515.6

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent PKC inhibitor (IC50 values are 6, 39, 83 and 110 nM for PKC , PKC , PKC and PKC , respectively). Suppresses proliferation and induces apoptosis in HCT116 colon carcinoma and U87MG glioblastoma cells in vitro . Reduces tumor growth and exhibits antiangiogenic activity in HT-29 colon carcinoma xenografts in mice. Also suppresses growth of HCT116 and U87MG xenografts in mice. Orally active.

catalog number base :

5994

product keywords :

Potent PKCbeta PKCb PKC inhibitors inhibits antitumor orally active protein kinases-C LY317615 Protein Kinase C 5994,

extended description :

Potent PKC inhibitor

chemical name text :

3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione

formula :

C 32 H 29 N 5 O 2

formula text :

C32H29N5O2

cas num :

170364-57-5

2020 USD :

142

2021 USD :

145 USD

alt names :

LY317615

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage