CP 673451 | Tocris Bioscience 5993/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 673451

catalog :

5993/10

quantity :

10 mg

price :

307 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Shi A, Li J, Qiu X, Sabbah M, Boroumand S, Huang T, et al. TGF-β loaded exosome enhances ischemic wound healing in vitro and in vivo. Theranostics. 2021;11:6616-6631 pubmed publisher
Frumm S, Yu S, Chang J, Artichoker J, Scaria S, Lee K, et al. A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane. Cell Stem Cell. 2021;28:315-330.e5 pubmed publisher

product information

brand :

Tocris

catalog number base :

5993

SKU :

5993/10

product name :

CP 673451

units size :

10 mg

description :

Potent and selective PDGFR inhibitor

target :

PDGF Receptor Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

417.5

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CP 673451 is a potent and selective PDGFR inhibitor (IC50 values are 1 and 10 nM for PDGFR- and - respectively). Selective for PDGFR kinase over a range of related kinases. Inhibits PDGFR- phosphorylation in glioblastoma xenografts and PDGF-induced angiogenesis in mice.

top caption :

Potent and selective PDGFR inhibitor

extended description :

Potent and selective PDGFR inhibitor

chemical name text :

1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine

formula :

C24H27N5O2

formula text :

C24H27N5O2

cas num :

343787-29-1

USD :

307 USD

product details :

Potent and selective PDGFR inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage