product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(+/-)-ML 209
catalog :
5987/10
quantity :
10 mg (also 50 mg)
price :
250 USD
more info or order :
image
image 1 :

Cat.No. 5987 - (?)-ML 209 C25H31NO6 CAS No. 1334526-14-5
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5987
SKU :
5987/10
product name :
(+/-)-ML 209
description :
ROR t inverse agonist; suppresses Th17 cell differentiation
target :
ROR / NR1F Inverse Agonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
441.52
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( )-ML 209 is a ROR t inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro . Does not suppress transcription of ROR . Minimal activity displayed on ER , LXR and thyroid hormone receptors (IC50 values 4.4 M).
product keywords :
ROR t inverse agonists agonism Th17 cell differentiation t helper cells inhibitor inhibits MS multiple sclerosis Retinoic Acid-related Orphan Receptors 5987,
extended description :
ROR t inverse agonist; suppresses Th17 cell differentiation
chemical name text :
3-(1,3-Benzodioxol-5-yl)-1-(cis-3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone
formula :
C25H31NO6
formula text :
C25H31NO6
cas num :
1334526-14-5
USD :
247
USD 2025 :
250 USD
product details :
ROR t inverse agonist; suppresses Th17 cell differentiation
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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