LY 2955303 | Tocris Bioscience 5984/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 2955303

catalog :

5984/5

quantity :

5 mg (also 25 mg)

price :

95 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Yamakawa K, Koyanagi Aoi M, Machinaga A, Kakiuchi N, Hirano T, Kodama Y, et al. Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase. Cancer Cell Int. 2023;23:94 pubmed publisher

image

image 1 :

Cat.No. 5984 - LY 2955303 C36H42N4O3 CAS No. 1433497-19-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5984

SKU :

5984/5

product name :

LY 2955303

description :

High affinity and selective RAR antagonist

target :

Retinoic Acid Receptor Antagonists

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

578.74

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LY 2955303 is a high affinity and selective RAR antagonist (Ki values are 1.1 nM, 1.7 M and 2.9 M for RAR , RAR and RAR respectively). Displays analgesic efficacy in a mouse model of osteoarthritis-like joint pain.

product keywords :

LY2955303 selective retinoic acid receptor gamma RARg antagonists antagonism osteoarthritis high affinity Retinoic Acid Receptors 5984,

extended description :

High affinity and selective RAR antagonist

chemical name text :

4-[5-[3,5-Bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]benzoic acid

formula :

C36H42N4O3

formula text :

C36H42N4O3

cas num :

1433497-19-8

USD :

USD 2025 :

95 USD

product details :

High affinity and selective RAR antagonist

more info or order :

Tocris Bioscience product webpage