chemical

Itraconazole

5981

50 mg

63 USD

5981

5981/50

Itraconazole

SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)

Smoothened Receptor Antagonists

Small Molecules

50 mg

99%

705.63

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SMO antagonist (IC50 = 690 nM); acts at different binding site to cyclopamine (Cat. No. 1623). Also cytochrome p450 inhibitor (IC50 = 16-26 nM). Inhibits cell cycle at G1 phase in vitro and blocks angiogenesis in vivo (IC50 = 160 nM). Antifungal.

5981

SMO antagonists smoothened receptors cytochrome p450 inhiibitors inhibits cell cycle angiogenesis antifungals hedgehog Smoothened Receptors Antiangiogenics Cell Cycle Inhibitors Antifungals 5981,

SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)

4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

C 35 H 38 Cl 2 N 8 O 4

C35H38Cl2N8O4

84625-61-6

61

63 USD

Store at -20°C