Itraconazole | Tocris Bioscience 5981/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Itraconazole

catalog :

5981/50

quantity :

50 mg

price :

74 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5981

SKU :

5981/50

rank :

0.0006

product name :

Itraconazole

description :

SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)

target :

Smoothened Receptor Antagonists

category :

Small Molecules

sizes available :

50 mg

url print :

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details of functionality :

Itraconazole is a SMO antagonist (IC50 = 690 nM); acts at different binding site to cyclopamine (Cat. No. 1623). Also cytochrome p450 inhibitor (IC50 = 16-26 nM). Inhibits cell cycle at G1 phase in vitro and blocks angiogenesis in vivo (IC50 = 160 nM). Antifungal.

extended description :

SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)

chemical name text :

4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

formula :

C 35 H 38 Cl 2 N 8 O 4

formula text :

C35H38Cl2N8O4

cas num :

84625-61-6

USD :

74 USD

product details :

SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage