CP 724714 | Tocris Bioscience 5973 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 724714

catalog :

5973

quantity :

10 mg (also 50 mg)

price :

193 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5973

SKU :

5973/10

product name :

CP 724714

description :

Potent and selective ErbB2 inhibitor

target :

EGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

469.53

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ErbB2 inhibitor (IC50 = 10 nM). Exhibits 500-1000-fold selectivity for ErbB2 over ErbB1 and other related RTKs. Induces G1 cell cycle arrest in an ErbB2-overexpressing human cancer cell line. Promotes tumor apoptosis. Induces tumor regression in a human tumor xenograft model. Displays no apparent toxic effect on cardiac tissue.

catalog number base :

5973

product keywords :

CP724714 HER2 ErbB2 inhibitors inhibits breast cancer tumour tumor apoptosis potent selective EGFR Apoptosis Inducers 5973,

extended description :

Potent and selective ErbB2 inhibitor

chemical name text :

2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide

formula :

C 27 H 27 N 5 O 3

formula text :

C27H27N5O3

cas num :

383432-38-0

2020 USD :

189

2021 USD :

193 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage