BAY 299 | Tocris Bioscience 5970 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 299

catalog :

5970

quantity :

25 mg

price :

318 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5970

SKU :

5970/25

product name :

BAY 299

description :

Potent and selective BRD1 and TAF1 inhibitor

target :

Bromodomain Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

429.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective BRD1 and TAF1 inhibitor (IC50 values are 6-67 and 8-13 nM, respectively). Displays selectivity over other bromodomains ( 30-fold over other members of the BRPF family; BRD9 and ATAD2; 300-fold over BRD4). Displays BRD1 and TAF1 inhibition in a NanoBRET cell assay. Inhibits binding of BRD1 and TAF1 to histone H4 (IC50 values are 575 nM and 0.9 M, respectively) and histone H3.3 (IC50 values are 825 nM and 1.4 M, respectively).

catalog number base :

5970

product keywords :

BAY299 potent BRD1 TAF1 inhibitors inhibits bromodomains and PHD Finger Transcription initiation factor TFIID subunits 1 Bromodomains 5970,

extended description :

Potent and selective BRD1 and TAF1 inhibitor

chemical name text :

6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

formula :

C 25 H 23 N 3 O 4

formula text :

C25H23N3O4

cas num :

2080306-23-4

2020 USD :

305

2021 USD :

318 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage