BAY 299 | Tocris Bioscience 5970/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 299

catalog :

5970/5

quantity :

5 mg (also 25 mg)

price :

90 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5970 - BAY 299 C25H23N3O4 CAS No. 2080306-23-4

product information

brand :

Tocris

catalog number base :

5970

SKU :

5970/5

product name :

BAY 299

units size :

5 mg (also 25 mg)

description :

Potent and selective BRD1 and TAF1 inhibitor

target :

Bromodomain Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

429.47

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BAY 299 is a potent and selective BRD1 and TAF1 inhibitor (IC50 values are 6-67 and 8-13 nM, respectively). Displays selectivity over other bromodomains ( 30-fold over other members of the BRPF family; BRD9 and ATAD2; 300-fold over BRD4). Displays BRD1 and TAF1 inhibition in a NanoBRET cell assay. Inhibits binding of BRD1 and TAF1 to histone H4 (IC50 values are 575 nM and 0.9 M, respectively) and histone H3.3 (IC50 values are 825 nM and 1.4 M, respectively).

top caption :

Potent and selective BRD1 and TAF1 inhibitor

extended description :

Potent and selective BRD1 and TAF1 inhibitor

chemical name text :

6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

formula :

C25H23N3O4

formula text :

C25H23N3O4

cas num :

2080306-23-4

USD :

90 USD

product details :

Potent and selective BRD1 and TAF1 inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage