Ro 3280 | Tocris Bioscience 5968 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ro 3280

catalog :

5968

quantity :

10 mg (also 50 mg)

price :

247 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5968

SKU :

5968/10

product name :

Ro 3280

description :

Potent and selective PLK1 inhibitor

target :

Polo-like Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

543.61

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective PLK inhibitor (IC50 = 3 nM). Exhibits selectivity for PLK1 over a panel of other kinases. Inhibits growth of a range of tumor cells lines in vitro and induces apoptosis in leukemia cells. Exhibits antitumor activity in mouse colorectal and nasopharyngeal cancer models in vivo .

catalog number base :

5968

product keywords :

Ro3280 Polo-like kinases inhibitors inhibits apoptosis inducers anticancer PLK1 potent selective Polo-like Kinase Mitosis 5968,

extended description :

Potent and selective PLK1 inhibitor

chemical name text :

4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)benzamide

formula :

C 27 H 35 F 2 N 7 O 3

formula text :

C27H35F2N7O3

cas num :

1062243-51-9

2020 USD :

247

2021 USD :

247 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage