SI-2 hydrochloride | Tocris Bioscience 5964/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SI-2 hydrochloride

catalog :

5964/10

quantity :

10 mg (also 50 mg)

price :

201 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhang H, Han W, Du Y, Zhao B, Yang P, Yin D. SRC3 acetylates calmodulin in the mouse brain to regulate synaptic plasticity and fear learning. J Biol Chem. 2021;297:101044 pubmed publisher

image

image 1 :

Cat.No. 5964 - SI-2 hydrochloride C15H15N5.HCl

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5964

SKU :

5964/10

product name :

SI-2 hydrochloride

description :

Steroid receptor coactivator 3 (SRC-3) inhibitor

target :

Additional Nuclear Receptor Compounds

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

301.78

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SI-2 hydrochloride is a potent steroid receptor coactivator 3 (SRC-3) inhibitor. Reduces SRC1, SRC2 and SRC3 levels in breast cancer cell lines. Inhibits cell growth (IC50 = 3.4 nM), induces apoptosis and attenuates migration of MDA-MB48 breast cancer cells in vitro . Inhibits tumor growth in a MDA-MB48 cell breast cancer mouse model. Orally available.

product keywords :

steroid receptor coactivator-3 SRC3 inhibitors inhibits breast cancers orally available 223788-33-8 Other Nuclear Receptors Histone Acetyltransferases Other Transcription Factors 5964,

extended description :

Steroid receptor coactivator 3 (SRC-3) inhibitor

chemical name text :

1-(2-Pyridinyl)ethanone 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone hydrochloride

formula :

C 15 H 15 N 5 .HCl

formula text :

C15H15N5.HCl

USD :

223

USD 2025 :

201 USD

product details :

Steroid receptor coactivator 3 (SRC-3) inhibitor

more info or order :

Tocris Bioscience product webpage