CMPI hydrochloride | Tocris Bioscience 5963 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CMPI hydrochloride

catalog :

5963

quantity :

10 mg

price :

191 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5963

SKU :

5963/10

product name :

CMPI hydrochloride

description :

Potent positive allosteric modulator of 4 2 nAChRs; also inhibitor of ( 4)2( 2)3, muscle-type and Torpedo nAChRs

target :

Nicotinic (a4b2) Receptor Agonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

379.28

url print :

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details of functionality :

Potent positive allosteric modulator of 4 2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for h 4 2 over h 3 2, h 3 4 and h 7. Inhibits ( 4)2( 2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 M, respectively), but not ( 4)3( 2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains.

catalog number base :

5963

product keywords :

PAM positive allosteric modulator Inhibitors inhibits CMPI nAChR nAChRs a4b2 alpha4beta2 4 2 nicotinic acetylcholine receptors photoreactive Nicotinic (a4b2) Receptors Nicotinic Receptors (Other Subtypes) 5963,

extended description :

Potent positive allosteric modulator of 4 2 nAChRs; also inhibitor of ( 4)2( 2)3, muscle-type and Torpedo nAChRs

chemical name text :

3-(2-Chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole hydrochloride

formula :

C 18 H 19 ClN 4 O.HCl

formula text :

C18H19ClN4O.HCl

2020 USD :

183

2021 USD :

191 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage