CMPI hydrochloride | Tocris Bioscience 5963/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CMPI hydrochloride

catalog :

5963/10

quantity :

10 mg

price :

215 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5963 - CMPI hydrochloride C18H19ClN4O.HCl

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5963

SKU :

5963/10

product name :

CMPI hydrochloride

description :

Potent positive allosteric modulator of 4 2 nAChRs; also inhibitor of ( 4)2( 2)3, muscle-type and Torpedo nAChRs

target :

Nicotinic (a4b2) Receptor Agonists

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

379.28

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CMPI hydrochloride is a potent positive allosteric modulator of 4 2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for h 4 2 over h 3 2, h 3 4 and h 7. Inhibits ( 4)2( 2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 M, respectively), but not ( 4)3( 2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains.

product keywords :

PAM positive allosteric modulator Inhibitors inhibits CMPI nAChR nAChRs a4b2 alpha4beta2 4 2 nicotinic acetylcholine receptors photoreactive Nicotinic (a4b2) Receptors Nicotinic Receptors (Other Subtypes) 5963,

extended description :

Potent positive allosteric modulator of 4 2 nAChRs; also inhibitor of ( 4)2( 2)3, muscle-type and Torpedo nAChRs

chemical name text :

3-(2-Chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole hydrochloride

formula :

C18H19ClN4O.HCl

formula text :

C18H19ClN4O.HCl

cas num :

2250025-94-4

USD :

238

USD 2025 :

215 USD

product details :

Potent positive allosteric modulator of 4 2 nAChRs; also inhibitor of ( 4)2( 2)3, muscle-type and Torpedo nAChRs

more info or order :

Tocris Bioscience product webpage