G10 | Tocris Bioscience 5944 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

G10

catalog :

5944

quantity :

10 mg (also 50 mg)

price :

140 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Sali T, Pryke K, Abraham J, Liu A, Archer I, Broeckel R, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015;11:e1005324 pubmed publisher

product information

brand :

Tocris

master code :

5944

SKU :

5944/10

product name :

G10

description :

Activator of STING-dependent signaling

target :

STING/TMEM173

category :

Small Molecules

unit size :

10 mg (also 50 mg)

main entrez gene id :

340061

purity :

98%

observed molecular weight :

430.88

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFN and IFN gene expression in human fibroblasts. Exhibits no effect on NF- B signaling. Blocks viral replication in vitro .

catalog number base :

5944

product keywords :

STING-dependent signaling activators activates interferons IRF3 antiviral STING-Dependent Signaling 5944, TMEM 173, MHC-II, MHC, interferon, IFN, IFN-alpha, IFN-beta, IFN-a, IFN-b, cytokine, cytokines

extended description :

Activator of STING-dependent signaling

chemical name text :

4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide

formula :

C 21 H 16 ClFN 2 O 3 S

formula text :

C21H16ClFN2O3S

cas num :

702662-50-8

2020 USD :

135

2021 USD :

140 USD

alt names :

endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, SAVI, Stimulator of interferon genes protein, stimulator of interferon protein, sting, STING-beta, TMEM173, transmembrane protein 173

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage