G10 | Tocris Bioscience 5944/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

G10

catalog :

5944/10

quantity :

10 mg (also 50 mg)

price :

174 USD

citations: 1

Reference
Sali T, Pryke K, Abraham J, Liu A, Archer I, Broeckel R, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015;11:e1005324 pubmed publisher

product information

brand :

Tocris

MasterCode :

5944

SKU :

5944/10

product name :

G10

target :

STING/TMEM173

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

430.88

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

G10 is an activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFN and IFN gene expression in human fibroblasts. Exhibits no effect on NF- B signaling. Blocks viral replication in vitro .

extended description :

Activator of STING-dependent signaling

chemical name text :

4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide

formula :

C 21 H 16 ClFN 2 O 3 S

formula text :

C21H16ClFN2O3S

cas num :

702662-50-8

USD :

174 USD

product details :

Activator of STING-dependent signaling

alt names :

endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, SAVI, Stimulator of interferon genes protein, stimulator of interferon protein, sting, STING-beta, TMEM173, transmembrane protein 173

storage :

Store at -20°C