PBIT | Tocris Bioscience 5930 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PBIT

catalog :

5930

quantity :

10 mg (also 50 mg)

price :

112 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5930

SKU :

5930/10

product name :

PBIT

description :

JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor

target :

Histone Demethylase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

241.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor (IC50 values are 3, 4.9 and 6 M for JARID1B, 1A and 1C, respectively). Selective for JARID1 over UTX and JMJD3. Increases levels of methylated H3K4 in JARIDB1-transfected HeLa cells and MCF7 cells. Inhibits proliferation of breast cancer cell lines expressing high levels of JARIDB1.

catalog number base :

5930

product keywords :

Jumonji AT-Rich Interactive Domain 1 JARID1B histone lysine demethylase inhibitors inhibits breast cancer Histone Demethylases 5930,

extended description :

JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor

chemical name text :

2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one

formula :

C 14 H 11 NOS

formula text :

C14H11NOS

cas num :

2514-30-9

2020 USD :

109

2021 USD :

112 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage