product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
CRT 0066854 hydrochloride
catalog :
5922/10
quantity :
10 mg (also 50 mg)
price :
322 USD
more info or order :
citations: 1
Reference
Kenchappa R, Liu Y, Argenziano M, Banu M, Mladek A, West R, et al. Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities. Cell Rep. 2021;37:110054 pubmed publisher
image
image 1 :
Tocris Bioscience 5922/10 image 1
Cat.No. 5922 - CRT 0066854 hydrochloride C24H25N5S.2HCl CAS No. 2250019-91-9
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5922
SKU :
5922/10
product name :
CRT 0066854 hydrochloride
description :
PKC and PKC inhibitor
target :
Protein Kinase C Inhibitors
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
95%
storage :
Store at -20°C
observed molecular weight :
488.48
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CRT 0066854 hydrochloride is a protein kinase C (PKC) inhibitor. Inhibits PKC and PKC (IC50 values are 132 and 639 nM, respectively). Restores polarized morphogenesis in oncogene expressing MDCK cells, decreases colony formation in HeLa cells and inhibits lethal giant larvae 2 (LLGL2) phosphorylation.
product keywords :
CRT0066854 HCl PKCiota inhibitors inhibits protein kinase C iota PKCzeta Protein Kinase C 5922,
extended description :
PKC and PKC inhibitor
chemical name text :
(2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine dihydrochloride
formula :
C24H25N5S.2HCl
formula text :
C24H25N5S.2HCl
cas num :
2250019-91-9
USD :
318
USD 2025 :
322 USD
product details :
PKC and PKC inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK