D9 | Tocris Bioscience 5921 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

catalog :

5921

quantity :

10 mg (also 50 mg)

price :

105 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Wang X, Mick G, McCormick K. Pyridine nucleotide regulation of hepatic endoplasmic reticulum calcium uptake. Physiol Rep. 2019;7:e14151 pubmed publisher

product information

brand :

Tocris

master code :

5921

SKU :

5921/10

product name :

description :

Potent thioredoxin reductase (TrxR) inhibitor

target :

Other Reductase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

596.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent thioredoxin reductase (TrxR) inhibitor (EC50 = 2.8 nM, IC50 = 0.03 and 0.1 M in MCF-7 cells and HT-29 cells, respectively). Highly stable in vivo ; exhibits no significant ligand exchange with albumin. Inhibits tumor proliferation in vitro and in vivo by inducing cell death. Selectively kills cancer cells.

catalog number base :

5921

product keywords :

Thioredoxin reductase TrxR inhibitors inhibits anti-tumor cancer gold Au Thioredoxin Reductases 5921,

extended description :

Potent thioredoxin reductase (TrxR) inhibitor

chemical name text :

(Diphenyl-2-thienylphosphine- P)[2-(4-methoxyphenyl)ethynyl]gold

formula :

C 25 H 20 AuOPS

formula text :

C25H20AuOPS

cas num :

1527513-89-8

2020 USD :

101

2021 USD :

105 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage