Ro 6842262 | Tocris Bioscience 5913/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ro 6842262

catalog :

5913/10

quantity :

10 mg (also 50 mg)

price :

299 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ojasalu K, Lieber S, Sokol A, Nist A, Stiewe T, Bullwinkel I, et al. The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis. Theranostics. 2023;13:1921-1948 pubmed publisher

image

image 1 :

Cat.No. 5913 - Ro 6842262 C28H26N4O4 CAS No. 1396006-71-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5913

SKU :

5913/10

product name :

Ro 6842262

description :

Potent LPA1 antagonist

target :

Lysophosphatidic Acid (LPA) Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

482.53

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ro 6842262 is a potent LPA1 antagonist (IC50 = 25 nM). Exhibits 1,200-fold selectivity for LPA1 over LPA3. Attenuates NHLF human lung fibroblast cell proliferation and contraction in vitro . Also reduces plasma histamine levels in mouse LPA-challenge model. Orally bioavailable.

product keywords :

Ro6842262 potent LPA1 lysophosphatidic acid receptor-1 antagonists idiopathic pulmonary fibrosis IPF Lysophosphatidic Acid Receptors 5913,

extended description :

Potent LPA1 antagonist

chemical name text :

1-[4 -[4-Methyl-5-[[[(1R)-1-phenylethoxy]carbonylamino]-1H-1,2,3-triazol-1-yl][1,1 -biphenyl]-4-yl]cyclopropanecarboxylic acid

formula :

C28H26N4O4

formula text :

C28H26N4O4

cas num :

1396006-71-5

USD :

296

USD 2025 :

299 USD

product details :

Potent LPA1 antagonist

more info or order :

Tocris Bioscience product webpage