TL4-12 | Tocris Bioscience 5910/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TL4-12

catalog :

5910/10

quantity :

10 mg (also 50 mg)

price :

224 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5910 - TL4-12 C25H27F3N6O2 CAS No. 1620820-12-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5910

SKU :

5910/10

product name :

TL4-12

description :

Potent MAP4K2 (GCK) inhibitor

target :

Other Kinase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

500.53

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TL4-12 is a potent MAP4K2 (GCK) inhibitor (IC50 = 37 nM). Exhibits 70-fold selectivity for MAP4K2 over TAK1 (IC50 = 2.7 M for TAK1). Inhibits IL-1 and TGF -induced p38 MAPK phosphorylation, in vitro .

product keywords :

MAP4K2 inhibitors inhibits mitogen activated protein kinase potent Other MAPK 5910,

extended description :

Potent MAP4K2 (GCK) inhibitor

chemical name text :

4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide

formula :

C25H27F3N6O2

formula text :

C25H27F3N6O2

cas num :

1620820-12-3

USD :

248

USD 2025 :

224 USD

product details :

Potent MAP4K2 (GCK) inhibitor

more info or order :

Tocris Bioscience product webpage