product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Bis-ANS
catalog :
5908
quantity :
10 mg
price :
149 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
5908
SKU :
5908/10
product name :
Bis-ANS
description :
Fluorescent probe for nonpolar cavities in proteins; used to detect A fibres
target :
Other Fluorescent Probes
category :
Small Molecules
unit size :
10 mg
purity :
97%
observed molecular weight :
672.85
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Fluorescent probe for nonpolar cavities in proteins. Used to detect A fibre (Kd = ~80 nM); exhibits distinct fluorescent profiles for fibres and oligomers. Fluoresces in hydrophobic environments, negligible fluorescence in water solutions. Excitation emission ~ 355 520 nm at pH 7.4. Also modulates liquid-liquid phase separation (LLPS) of TDP-43 low complexitry domain in vitro . Displays biphasic modulation; promotes LLPS at low concentrations but disprut liquid droplets at higher concentrations.
catalog number base :
5908
product keywords :
Amyloid A peptides fibers fibres oligomers oligomeric fluorescent probe detects LLPS liquid phase separation Amyloid Beta Peptides Fluorescent Amyloid B Probes 5908,
extended description :
Fluorescent probe for nonpolar cavities in proteins; used to detect A fibres
chemical name text :
4,4 -Bis(phenylamino)-[1,1 -binaphthalene]-5,5 -disulfonic acid dipotassium salt
formula :
C 32 H 22 K 2 N 2 O 6 S 2
formula text :
C32H22K2N2O6S2
cas num :
65664-81-5
2020 USD :
144
2021 USD :
149 USD
storage :
Store at RT
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK