chemical

Imatinib mesylate

5906/100

100 mg

134 USD

5906

5906/100

0.061

Imatinib mesylate

Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Abl Kinase Inhibitors

Small Molecules

100 mg

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Imatinib mesylate is a potent and selective v-Abl tyrosine kinase inhibitor (IC50 = 38 nM). Also inhibits PDGFR and c-kit. Exhibits selectivity for v-Abl over a panel of other tyrosine and serine/threonine protein kinases. Selectively inhibits PDGF-stimulated growth of v- abl -transformed PB-3 cells and v- sis -transformed BALB/c 3T3 cells in vitro . Exhibits antitumor effects in mice bearing AMuLV or BABL/c 3T3 v- sis cells. Inhibits replication of SARS-CoV and MERS-CoV in vitro (EC50 values are 9.823 and 17.689 M, respectively).

Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate

C 29 H 31 N 7 O.CH 4 O 3 S

C29H31N7O.CH4O3S

220127-57-1

134 USD

Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Gleevec, CGP 57148B

Store the unopened product at 2 - 8 °C. Do not use past expiration date.