Montelukast sodium | Tocris Bioscience 5904/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Montelukast sodium

catalog :

5904/10

quantity :

10 mg (also 50 mg)

price :

96 USD

citations: 1

Reference
Wright P, McCoull D, Walsh Y, Large J, Hadrys B, Gaurilcikaite E, et al. Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2. Biochem Biophys Res Commun. 2019;520:35-40 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5904

SKU :

5904/10

product name :

Montelukast sodium

description :

CysLT1 and GPR17 antagonist

target :

Leukotriene and Related Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Desiccate at RT

observed molecular weight :

608.17

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Montelukast sodium is a cysteinyl leukotriene receptor 1 (CysLT1) and GPR17 antagonist. Blocks pentylenetetrazole -induced seizures, blood brain barrier (BBB) disruption and leukocyte migration in mice. Reduces neuroinflammation, improves BBB integrity, enhances learning and memory, and restores hippocampal neurogenesis and cognitive function in aged rats. Orally active and brain penetrant.

product keywords :

Leukotriene D4 antagonists antagonism cysteinyl receptors CysLT1 seizures blood brain barrier disruption epilepsy GPR17 Leukotriene and Related Receptors 5904,

extended description :

CysLT1 and GPR17 antagonist

chemical name text :

1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt

formula :

C35H35ClNNaO3S

formula text :

C35H35ClNNaO3S

cas num :

151767-02-1

USD :

106

USD 2025 :

96 USD

product details :

CysLT1 and GPR17 antagonist