AZ 10397767 | Tocris Bioscience 5872 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZ 10397767

catalog :

5872

quantity :

10 mg (also 50 mg)

price :

235 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5872

SKU :

5872/10

product name :

AZ 10397767

description :

Potent CXCR2 antagonist

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

400.88

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF- B activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.

catalog number base :

5872

product keywords :

AZ10397767 chemokine cxc receptors antagonists antagonism orally bioavailable potent selective Chemokine CXC Receptors 5872,

extended description :

Potent CXCR2 antagonist

chemical name text :

5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one

formula :

C 15 H 14 ClFN 4 O 2 S 2

formula text :

C15H14ClFN4O2S2

cas num :

333742-63-5

2020 USD :

228

2021 USD :

235 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage