AZ 10397767 | Tocris Bioscience 5872/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZ 10397767

catalog :

5872/10

quantity :

10 mg (also 50 mg)

price :

263 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5872 - AZ 10397767 C15H14ClFN4O2S2 CAS No. 333742-63-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5872

SKU :

5872/10

product name :

AZ 10397767

description :

Potent CXCR2 antagonist

target :

Chemokine Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

400.88

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF- B activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.

product keywords :

AZ10397767 chemokine cxc receptors antagonists antagonism orally bioavailable potent selective Chemokine CXC Receptors 5872,

extended description :

Potent CXCR2 antagonist

chemical name text :

5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one

formula :

C15H14ClFN4O2S2

formula text :

C15H14ClFN4O2S2

cas num :

333742-63-5

USD :

292

USD 2025 :

263 USD

product details :

Potent CXCR2 antagonist

more info or order :

Tocris Bioscience product webpage