CDN 1163 | Tocris Bioscience 5869/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CDN 1163

catalog :

5869/10

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ferdek P, Jakubowska M, Nicolaou P, Gerasimenko J, Gerasimenko O, Petersen O. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides. Cell Death Dis. 2017;8:e2640 pubmed publisher

image

image 1 :

Cat.No. 5869 - CDN 1163 C20H20N2O2 CAS No. 892711-75-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5869

SKU :

5869/10

product name :

CDN 1163

description :

SERCA2 allosteric activator

target :

Ca2+-ATPase Activators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

320.38

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CDN 1163 is a SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/ob mice. Neuroprotective, improves memory and cognition in a mouse Alzheimer s disease model and reduces dyskinesia in rat model of Parkinson's disease. Orally bioavailable.

product keywords :

CDN1163 allosteric activators sarco/endoplasmic reticulum Ca2+-ATPase activates ER stress SERCA2b type II diabetes T2D Ca2+-ATPase Other ER stress/UPR 5869,

extended description :

SERCA2 allosteric activator

chemical name text :

4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide

formula :

C20H20N2O2

formula text :

C20H20N2O2

cas num :

892711-75-0

USD :

202

USD 2025 :

205 USD

product details :

SERCA2 allosteric activator

more info or order :

Tocris Bioscience product webpage