PH 797804 | Tocris Bioscience 5866 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PH 797804

catalog :

5866

quantity :

10 mg (also 50 mg)

price :

210 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5866

SKU :

5866/10

product name :

PH 797804

description :

Potent and selective p38 / inhibitor

target :

p38 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

477.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective p38 / inhibitor (IC50 values are 26 and 102 nM, respectively). Exhibits 100-fold selectivity for p38 / over 71 other kinases, enzymes and GPCRs, including p38 , p38 , JNK and ERK2. Inhibits LPS-induced TNF production in U937 monocytes in vitro . Suppresses acute and chronic inflammatory responses in rat models of arthritis. Orally active. . PH 797804 is the (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer.

catalog number base :

5866

product keywords :

PH797804 potent selective p38a p38alpha p38b p38beta p38 p38 inhibitors inhibits anti-inflammatory p38 5866,

extended description :

Potent and selective p38 / inhibitor

chemical name text :

(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide

formula :

C 22 H 19 BrF 2 N 2 O 3

formula text :

C22H19BrF2N2O3

cas num :

1358027-80-1

2020 USD :

205

2021 USD :

210 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage