PH 797804 | Tocris Bioscience 5866/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PH 797804

catalog :

5866/10

quantity :

10 mg (also 50 mg)

price :

264 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5866 - PH 797804 C22H19BrF2N2O3 CAS No. 1358027-80-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5866

SKU :

5866/10

product name :

PH 797804

description :

Potent and selective p38 / inhibitor

target :

p38 Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

477.3

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PH 797804 is a potent and selective p38 / inhibitor (IC50 values are 26 and 102 nM, respectively). Exhibits 100-fold selectivity for p38 / over 71 other kinases, enzymes and GPCRs, including p38 , p38 , JNK and ERK2. Inhibits LPS-induced TNF production in U937 monocytes in vitro . Suppresses acute and chronic inflammatory responses in rat models of arthritis. Orally active. . PH 797804 is the (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer.

product keywords :

PH797804 potent selective p38a p38alpha p38b p38beta p38 p38 inhibitors inhibits anti-inflammatory p38 5866,

extended description :

Potent and selective p38 / inhibitor

chemical name text :

(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide

formula :

C22H19BrF2N2O3

formula text :

C22H19BrF2N2O3

cas num :

1358027-80-1

USD :

261

USD 2025 :

264 USD

product details :

Potent and selective p38 / inhibitor

more info or order :

Tocris Bioscience product webpage