chemical

Tolcapone

5864

10 mg (also 50 mg)

86 USD

5864

5864/10

Tolcapone

COMT inhibitor; also inhibits transthyretin aggregation

Catechol O-Methyltransferase (COMT) Inhibitors

Small Molecules

10 mg (also 50 mg)

99%

273.24

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COMT inhibitor. Inhibits both brain and peripheral COMT. Also binds transthyretin (TTR) with high affinity (Kd1 and Kd2 values are 21 and 58 nM, respectively). Inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro . Stabilizes TTR in mice and humans in vivo . Orally bioavailable.

5864

catechol O-methyl transferase inhibitors inhibits COMT orally bioavailable high affinity TTR binding transthyretin aggregation Ro40-7592 Tasmar Ro 40-7592 Catechol O-Methyltransferase 5864, Breast Cancer, Schizophrenia, Parkinsons, Catechol O-Methyltransferase, Catechol O Methyltransferase, O-methylation catecholamines, catecholamine, dopamine, epinephrine, norepinephrine, adrenalin, noradrenalin, L-DOPA, alpha-methyl DOPA, isoproterenol

COMT inhibitor; also inhibits transthyretin aggregation

(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone

C 14 H 11 NO 5

C14H11NO5

134308-13-7

83

86 USD

Tasmar, Ro 40-7592

Store at +4°C