7rh | Tocris Bioscience 5860 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7rh

catalog :

5860

quantity :

5 mg

price :

169 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5860 - 7rh C30H29F3N6O CAS No. 1429617-90-2

product information

brand :

Tocris

master code :

5860

SKU :

5860/5

product name :

7rh

description :

Potent and selective DDR1 inhibitor; orally bioavailable

target :

Additional RTK Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

546.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective DDR1 inhibitor (IC50 = 6.8 nM). Exhibits selectivity for DDR1 over DDR2, Bcr-Abl and c-Kit (IC50 values are 101.4 and 355 nM and 10 M, respectively) and a range of other kinases. Inhibits proliferation of cancer cell lines expressing high levels of DDR1 in vitro and suppresses cancer cell invasion, adhesion and tumorigenicity. Orally bioavailable.

catalog number base :

5860

product keywords :

Discoidin domain receptors 1 inhibitors inhibits potent selective DDR1 orally bioavailable Other RTKs 5860,

extended description :

Potent and selective DDR1 inhibitor; orally bioavailable

chemical name text :

4-Ethyl-N-[3-[(4-methyl-1-piperazinyl)methyl]-5-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)benzamide

formula :

C 30 H 29 F 3 N 6 O

formula text :

C30H29F3N6O

cas num :

1429617-90-2

2020 USD :

169

2021 USD :

169 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage