SR 9238 | Tocris Bioscience 5854 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SR 9238

catalog :

5854

quantity :

10 mg (also 50 mg)

price :

168 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bruschi F, Claudel T, Tardelli M, Starlinger P, Marra F, Trauner M. PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells. Hepatol Commun. 2019;3:1191-1204 pubmed publisher

product information

brand :

Tocris

master code :

5854

SKU :

5854/10

product name :

SR 9238

description :

Potent and selective LXR inverse agonist

target :

LXR-like Receptor Inverse Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

595.73

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXR and LXR , respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hepatic steatosis in obese mice.

catalog number base :

5854

product keywords :

SR9238 potent selective LXR inverse agonist liver obesity receptors LXR-like Receptors 5854,

extended description :

Potent and selective LXR inverse agonist

chemical name text :

Ethyl 5-[[[[3 -(Methylsulfonyl)[1,1 -biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate

formula :

C 31 H 33 NO 7 S 2

formula text :

C31H33NO7S2

cas num :

1416153-62-2

2020 USD :

164

2021 USD :

168 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage