SR 9238 | Tocris Bioscience 5854/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SR 9238

catalog :

5854/10

quantity :

10 mg (also 50 mg)

price :

212 USD

citations: 2

Reference
Yuan B, Shi K, Zha J, Cai Y, Gu Y, Huang K, et al. Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway. Cell Death Dis. 2023;14:51 pubmed publisher
Bruschi F, Claudel T, Tardelli M, Starlinger P, Marra F, Trauner M. PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells. Hepatol Commun. 2019;3:1191-1204 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5854

SKU :

5854/10

product name :

SR 9238

description :

Potent and selective LXR inverse agonist

target :

LXR-like Receptor Inverse Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

595.73

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SR 9238 is a potent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXR and LXR , respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hepatic steatosis in obese mice.

product keywords :

SR9238 potent selective LXR inverse agonist liver obesity receptors LXR-like Receptors 5854,

extended description :

Potent and selective LXR inverse agonist

chemical name text :

Ethyl 5-[[[[3 -(Methylsulfonyl)[1,1 -biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate

formula :

C31H33NO7S2

formula text :

C31H33NO7S2

cas num :

1416153-62-2

USD :

209

USD 2025 :

212 USD

product details :

Potent and selective LXR inverse agonist