ZLD 1039 | Tocris Bioscience 5847 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZLD 1039

catalog :

5847

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5847

SKU :

5847/10

product name :

ZLD 1039

description :

Potent and selective EZH2 inhibitor; orally bioavailable

target :

EZH2 Inhibitor

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

612.8

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective EZH2 inhibitor (IC50 = 5.6 nM). Displays selectivity for EZH2 over a panel of HMTs (inhibition less than 30% at 16 M). Blocks H3K27 methylation in breast cancer cell lines. Induces tumor regression and metastasis in breast cancer xenograft-bearing mice. Reactivates silenced tumor suppressors in vivo . Orally bioavailable.

catalog number base :

5847

product keywords :

ZLD1039 Potent selective EZH2 inhibitors inhibits orally bioavailable H3K27 methylation EZH2 5847, EZH 2, ENX 1, ENX1, KMT6, KMT 6

extended description :

Potent and selective EZH2 inhibitor; orally bioavailable

chemical name text :

3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]benzamide

formula :

C 36 H 48 N 6 O 3

formula text :

C36H48N6O3

cas num :

1826865-46-6

2020 USD :

195

2021 USD :

195 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage