JX 06 | Tocris Bioscience 5845/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JX 06

catalog :

5845/10

quantity :

10 mg (also 50 mg)

price :

99 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5845

SKU :

5845/10

rank :

0.061

product name :

JX 06

description :

Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor

target :

PDK-1 Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JX 06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC50 values are 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively). Exhibits selectivity for PDK1/2/3 over PDK4 and a panel of 323 other kinases. Suppresses A549 lung cancer cell proliferation in vitro . Reduces tumor volume of A549 xenografts in mice.

extended description :

Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor

chemical name text :

Bis(morpholinothiocarbonyl) disulfide

formula :

C 10 H 16 N 2 O 2 S 4

formula text :

C10H16N2O2S4

cas num :

729-46-4

USD :

99 USD

product details :

Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage